I review the prospects of Dark Matter indirect detection in light of the latest observational results of gamma-ray experiments such as INTEGRAL (at energies around 1 MeV), HESS (above 1 TeV) and other ACTs. I will present an upper limit on the mass of "light dark matter", and discuss the implications of the HESS observation of the Galactic center. I will also present some new results on the combined effect of stellar collisions, annihilation, and adiabatic compression around the supermassive black hole at the Galactic center, on the distribution of Dark Matter in the innermost regions of the Galaxy.